Jalan Cerita:
While carrying on their usual hi-jinks, they inadvertantly stow-away on a spaceship bound for Mars. They meet up with the local Martian residents and cause them to invade the Earth, aided by the "Invincitron", a vacuum-wielding giant robot. Tom, Jerry and their Martian ally, Peep, save the day.

Pemain:

Jeff Bennett (suara) Dr. Gluckman / Martian Guard /#1 / President

Corey Burton (suara) Martian Scientist / Court Attendant / Eyes At Gate

Kathryn Fiore (suara) Peep / Press Girl

Brad Garrett (suara) Commander Bristle / Martian Guard /#3

Jess Harnell (suara) Major Buzz Blister / Martian General / Worker /#3